Los Andes is a town of craftsmen that work with Cala ceramic, producing hand-painted earthenware, jars and fonts, among other items.

The town, founded on July 31, 1791 with the name of Santa Rosa de los Andes, is 81 kilometers from Santiago. Among its attractions can be mentioned the Casa de los Villares, a mansion built at the end of the 19th century by one of the main families in the area, and the Carmelita de Auco Sanctuary, holding the remains of Sor Teresa de los Andes, the first Chilean saint, consecrated by Pope John Paul II on the occasion of his visit to Chile in 1987, and sanctified on May 21, 1993 in Rome.

Curacavi is a picturesque village located 47 kilometers from Santiago. It is noted for manufacturing sweet buns, chicha and for the proverbial hospitality of its population. This is an ideal trekking and horse riding area.

Pomaire, an old Indian town, probably of Peruvian origin, that still maintains ancient traditions and customs, which are reflected in its earthenware crafts and its tasty local cuisine including the exquisite "empanada pomairina" (Pomaire meat pie).

Besides these attractions, the area has theme trails like the "cheese and wine trail". A few kilometers away lies Lake Aculeo. It is located 60 kilometers west of Santiago.

Maipu Votive Temple, dedicated to the Virgen del Carmen, patron and "General" of Chile's armies, in thanks for the decisive victory on April 5, 1818 at Maipu in Chile's struggle for independence. To one side of the temple lies the Del Carmen Museum, with religious figures, colonial furniture and historical documents, as well as period carriages. More than 500,000 pilgrims visit this site every year. It lies a little over 10 kilometers from Santiago, in Maipu municipality.

Pukara de Chena, this is an Inca-style building from the 15th century, which is thought to have had a defensive purpose, due to its strategic placing on top of the Chena hill, that overlooks the whole Maipo river valley. It was only discovered in 1975, thanks to excavations and research by archaeologist Ruben Stehberg. It is at kilometer 13 of Route 5 South.

Calera de Tango, this is an architectural complex built in the Bavarian Jesuit colony formed by the Master's House, church and other surrounding buildings, around the year 1724. Thus, Calera de Tango became a center for evangelization and education in crafts and professions such as watch-making, sculpture, engraving and goldsmith work.

Declared a Historical Monument, it is one of the most important rural buildings of the central area. It is 7 kilometers southwest of Malloco and 15 kilometers southwest of Santiago.